Systemic Thrombolysis by Alteplase for Acute Ischemic Stroke


 Evidence was summarized to determine the effect of alteplase in adult stroke patients.
 There is substantial uncertainty concerning evidence due risk bias available studies and imprecision how magnitude treatment effects were estimated.
 The identified research suggests that administered within 3 hours a might result in:
 fewer deaths after 18 months little-to-no difference death 7 days, months, 6 or years
 increased brain bleeds days but no 36 months
 improvements functioning independence months; at some showed another study higher functioning.
 between 4.5 while other suggested more deaths
 differences hours; on bleeds, bleeds
 functioning, reported improved